Meddling with the Muddling Rushdie Affair

MUDdling Through

The worlds project is concerned with developing next-generation collaboration frameworks. We strohgly believe that real progress in enhancing the usability of collaborative systems hinges on improving our understanding of work, and applying the resulting insights to development of collaborative work support frameworks. We are investigating the thesis that appropriate bases for such an approach ...

My affair with the JAP.

DURING World War II, the US Army Quartermaster Corps established a Climatic Research Laboratory on the second floor of an old building of the Pacific Mills in Lawrence, MA, on the banks of the Merrimac River. The mission of this organization was to test equipment, particularly clothing, for the use of troops in the field, and the Pacific Mills had been chosen because it housed climatically cont...

The meddling microbes midst our medicines

It is not surprising that the complex metabolic machinery of the gut microbiome has accidental, or directed, ability to alter our medicines and influence their efficacy. What is not known is the extent to which this has contributed to drug failures or contraindications, or to the derailment of clinical trials. Some studies are unraveling the mechanisms by which the microbiota alter specific dru...

Muddling Through: Noisy Equilibrium Selection

This paper examines an evolutionary model in which the primary source of ``noise'' that moves the model between equilibria is not arbitrarily improbable mutations but mistakes in learning. We model strategy selection as a birth death process, allowing us to find a simple, closed-form solution for the stationary distribution. We examine equilibrium selection by considering the limiting case as t...

Dementia: still muddling along?